The sixth generation of the Regal was introduced in 2017 as a 2018 model-year, and it was based on the same platform as the European Opel/Vauxhall Insignia.

In 2008, Buick introduced a new generation of the Regal range to the North-American market. It was primarily based on the European Opel/Vauxhall Insignia. Four years later, it refreshed the lineup.

GM decided that it needed a facelifted version for the Buick's Regal lineup, and that came in 2012, four years after the model's introduction.

When GM designed a good car, it adapted it for various markets worldwide through its badge-engineering program. So it was the 2010 Buick Regal born as a European Vauxhall/Opel Insignia.

The fourth generation of the Buick Regal was launched in 1997 and it was marketed as a sports sedan vehicle. It shared the platform with the Oldsmobile Intrigue, Pontiac Grand Prix, Chevrolet Lumina and Chevrolet Monte Carlo.

Buick tried to conquer a more significant chunk of the market with the third generation of the Regal. It was introduced in 1987 as a 1988 model year.