The 2001 Chevrolet S10 pickup was produced on the same platform as the Chevrolet Blazer, a vehicle that made the transition from a rugged off-road vehicle to a comfortable SUV.

Chevrolet replaced the S10 lineup in 1994 in a few cab versions and refreshed the lineup several times until 2003 when it replaced the model with the Colorado.

Chevrolet introduced the second generation of the S10 pickup in 1994, giving up the squared shapes of the first generation, and making the car more family-friendly.